Wilson's Disease

Alternate Name: Hepatolenticular Degeneration

Test:

S.copper (AB). S.caeruloplasmin (L), U.copper(H)

Sign:

Ankle clonus, athetosis, nail discolouration, par-kinsonian facies, postural tremor, Kayser-Fle­ischer ring

Dd:

Other liver diseases, Parkinson's disease

Phys:

Familial disorder involving metabolism of copper, basal ganglia disease and liver cirrhosis