Alternate Name:
Test:
RBC (H), Hb (L), HbH (+ HbH thalassaemia)MCV (L), MCHC (L), B.target cells (+), marrow biopsy (AB), tissue DNA probe (+)
Sign:
South east Asian or Mediterranean origin
Dd:
Iron deficiency anaemia, haemoglobinopathies,sideroachrestic anaemia
Phys:
Due to a genetic defect, insufficient haemoglobin is produced. Thalassaemia major is the homozygous form
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