Spherocytosls, Hereditary

Alternate Name:

Test:

B.smear (spherocytic white cells), RCC (L), MCV:(L), MCHC (L), WCC (H), B.reticulocytes platelets (H), Hb (14; bone marrow (AB), S.biliru­bin (H), Coombs' test (-), osmotic fragility (H)

Sign:

Splenomegaly, jaundice, anaemia

Dd:

Autoimmune diseases, haemolytic anaemia, drugabuse, alcoholism

Phys:

Hereditary cell membrane defect that allows ex­cess entry of sodium into cells