Paget's Disease of Bone

Alternate Name: Osteitis Deformans

Test:

S.ALP (VH), S.ACP (H), U.calcium (H), S.calcium(N), S.phosphate (N), U.deoxypyridonoline (H), U.cross-linked N-telopeptides (+)

Sign:

mul-

Dd:

Metastatic carcinoma, hyperparathyroidism;mul-tiple myeloma, osteosarcoma

Phys:

Chronic, progressive disorder of bone causing gross bony deformities. Usually localised and asymmetrical