Multiple Sclerosis [MS]

Alternate Name: Disseminated Sclerosis

Test:

CSF protein (N or H), CSF cells (N or H), routine haematology (N), HLA-03 (+), S.IgG (Helectrophysiologicaltests (AB), MRI (AB)

Sign:

Ankle clones, peripheral reflexes abnormal,Babinski's sign, consensual reflex, nystagmus, papilloedema, flaccid or spastic paralysis, Rinne's test, scanning speech, intention tremor

Dd:

Cerebral tumours, cerebral degeneration, cere­brovascular disease, motor neurone disease, cer­vical spondylosis, neurosyphilis

Phys:

Demyelinating disorder of brain or cord giving wide variations in symptoms, signs, severity and prognosis