Lupus Erythematosus, Systemic [SLE]

Alternate Name: Disseminated Lupus Erythematosus

Test:

S.antinuclear antibodies (+), S.anti-DNA antibod-ies (+), S.HLA-DR3 (+), S.anti-dsDNA antibodiesScardiolipin autoantibodies (+), S.histone auto-antibodies (+ drug induced SLE), FANA (H),lupus anticoagulant antibodies (+), anti-Smith an­tibodies (H), B.LE cells (+), S. ANCA (H), S. com­plement C3 and C4 (H), DNA autoantibodies (+), S. ENA (H), S. WCC (L), Hb (L), VDRL (false +), platelets (L), S.albumin (N or L), S.garrima-globu­lin (N or H), LFT (AB), Coombs' test (+), U.proteih (+), ESR (H), CRP. (N), synovial fluid WBC (H), S.complement (L), U.microscopy (+ casts, + blood

Sign:

Butterfly rash, discoid rash, photosensitivity, oral ulcers, choreiform movements, hypertension, large kidney, pleural effusion, splenomegaly, pecia, multiple system lesions

Dd:

Rheumatoid arthritis, rheumatic fever, TB, sclero-derrne glomerulonephritis, syphilis, Sjogren% syn., dermatomyositis

Phys:

Chronic inflammatory condition of skin, joints, kid­neys and nervous system