Kala-azar

Alternate Name: Visceral Leishmaniasis

Test:

Spleen, liver or marrow biopsy (parasite isolated),specific immunological test (+), Hb (L), S.globulin (H), S.IgG (VH), WCC (L), platelets (L), B.mono­cytes (H), B.eosinophils (VL), ESR (H)

Sign:

Splenomegaly

Dd:

Malaria, leukaemia, cirrhosis, TB, typhoid, histo-plasmosis, brucellosis, schistosomiasis, septi­caemia, trypanosomiasis, endocarditis

Phys:

Infection by Leishmania donovani causes spleno­megaly, hepatomegaly, fever and lymphadenop­athy. Occurs in central Asia and Africa