Hepatitis A

Alternate Name: Acute Viral Infective Hepatitis

Test:

S.IgM antiHAV (+), S.IgM (H), B.AST (H), A.ALT(VH), S.bilirubin (H), B.ALP (H), WCC (N or L), U.bilirubin (H), U.protein (+), U.urobilinogen (H early)

Sign:

Jaundice, hepatomegaly, splenomegaly

Dd:

Hepatitis B, chronic active hepatitis Plus acute viral infectioni, infectious mononucle­osis, dengue fever, Q fever, malaria, yellow leve•, amoebiasis, drugs, toxins, leptospirosis, alcohol­ism, cirrhosis, biliary obstruction, pancreatic cat­cinoma, carotenaemia

Phys:

Hepatic cell necrosis causes release of enzymes and bilirubin into blood Viral infection of liver transmitted by food that causes severe damage and loss of function Incubation period 2-6 weeks Fulminant in 0.15% of cases Does not cause hepatic malignancy Vaccine available