Hepatitis, Chronic Active Autoimmune

Alternate Name:

Test:

S.AST (H to VH), S.ALP (H), S.albumin (N to L),ESR (VH), prothrombin index (H), S.IgG (H), S.antinuclear antibodies (+), S.anti-smooth mus-cle antibodies (+), S.HLA-B8 (+), S. HLA DRw3 (+)

Sign:

Spider naevi, buffalo hump, moon facies, abdomi­nal striae

Dd:

Chronic viral hepatitis, Wilson's disease, alco-holic liver disease, cirrhosis, alpha ,-antitrypsin deficiency, sclerosing cholangitis

Phys:

Chronic, progressive. More common in young women. Aetiology unknown