Coeliac Disease

Alternate Name: Non-tropical Sprue

Test:

Faecal fat (+), S.fasting folate (L), S.albumin,(L),S.cholesterol (L), HLA-B (+), HLA-DR3 (+), S;IgA (H or N), S.antigliaden IgA (H), xylose absorption test (+), S.calcium (L), S.carotene (L), S.reticular cell antibodies (t), Hb (L), S.iron (L)

Sign:

Dd:

Cystic fibrosis, Whipple's disease, disaccha:ride deficiency, othei' malabsorption syndromes

Phys:

An intolerance to gluten in wheat and rye causes small intestinal changes that impair absorption from the gut