Acquired Immune Deficiency Syndrome [AIDS]

Alternate Name:

Test: Group I (acute infection) S.HIV-3 (HTLV-3) antibodies (+), S.p24 antigen (+), S.p24 antibody (-), Hb (N), ESR (H or N), B.Iymphocytes (H), B.neutrophils (N), platelets (N), S.immunoglobulins (N), S.complement (N or H) Group II (asymptomatic) S.HIV-3 (HTLV-3) antibodies (+), S.p24 antigen (-), S.p24 antibody (+), Hb (N), ESR (N), B.lym¬phocytes (N), B.neutrophils (N), platelets (N), S.immunoglobulins (H), S.complement (H) Group III (persistent generalised lymphade-nopathy) S.HIV-3 (HTLV-3) antibodies (+), S.p24 antigen (-), S.p24 antibody (+), Hb (N), ESR (N), B.lym¬phocytes (N), B.neutrophils (N), platelets (N), S.irnmunoglobulins (H), S.complement (H) Group IV (AIDS related complex) S.HIV-3 (HTLV-3) antibodies (+), S.p24 antigen (+), S.p24 antibody (+), Hb (L), ESR (H), B.lym¬phocytes (L), B.neutrophils (L), platelets (L), S.im-munoglobulins (H), S.complement (H) Group IV (AIDS) S.HIV-3 (HTLV-3) antibodies (+), S.p24 antigen (+), S.p24 antibody (-), Hb (VL), ESR (VH), B.lym¬phocytes (VL), B.neutrophils (VL), platelets (VL), S.immunoglobulins (H), S.complement-(VH)

Sign: Fever, skin nodules, adenitis, spleriomavaly; oral candidiasis, hairy leucoplakia, sarcomas, absent reflexes

Dd: Idiopathic lymphadenopathy syn., viraemia, fungaemia, metastatic carcinoma, other causes of reduced immunity (see separate entry)

Phys: Caused by human immunodeficiency virus (HIV). Transmitted by blood and semen.Occurs mainly in homosexuals, IV drug users and blood product recipients. Mortality close to 100%