| Product | Precaution | Interaction | Onset | Severity |
|---|---|---|---|---|
| PHENYTOIN | Concurrent use of PHENYTOIN and FOOD may result in altered phenytoin concentrations. | FOOD | Rapid (within 24 hours) | Minor (little if any clinical effect) |
| PHENYTOIN | Concurrent use of PHENYTOIN and ENTERAL NUTRITION may result in decreased serum phenytoin levels and subsequently reduced therapeutic response to phenytoin. | ENTERAL NUTRITION | Rapid (within 24 hours) | Major (possibly life threatening or potential permanent damage |
| PHENYTOIN | Concurrent use of PHENYTOIN and ETHANOL may result in decreased phenytoin serum concentrations increased seizure potential, and additive CNS depressant effects. | ETHANOL | Rapid (within 24 hours) | Moderate (mayexacerbate patient’s condition) |
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