Drug Interaction Form

Drug Interactions Details

Product	Precaution	Interaction	Onset	Severity
CYCLOSPORINE	Concurrent use of CYCLOSPORINE and FOOD may result in increased peak cyclosporine concentrations.	FOOD	Rapid (within 24 hours)	Moderate (mayexacerbate patient’s condition)
CYCLOSPORINE	Concurrent use of CYCLOSPORINE and GRAPEFRUIT JUICE may result in cyclosporine toxicity (renal dysfunction, cholestasis, paresthesias).	GRAPEFRUIT JUICE	Delayed (after 24 hours)	Moderate (mayexacerbate patient’s condition)

Product

Precaution

Interaction

Onset

Severity

CYCLOSPORINE

Concurrent use of CYCLOSPORINE and FOOD may result in increased peak cyclosporine concentrations.

FOOD

Rapid (within 24 hours)

Moderate (mayexacerbate patient’s condition)

CYCLOSPORINE

Concurrent use of CYCLOSPORINE and GRAPEFRUIT JUICE may result in cyclosporine toxicity (renal dysfunction, cholestasis, paresthesias).

GRAPEFRUIT JUICE

Delayed (after 24 hours)

Moderate (mayexacerbate patient’s condition)

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