Indications & Dose:

INDICATIONS AND USES: Acne vulgaris (top formulations); rosacea (top formulations).

DOSE

TOP apply bid

Contraindications:

Regional enteritis, ulcerative colitis, antibiotic-associated colitis

Cautions:

Precautions:

History of GI disease, liver disease, renal disease, atopic individuals, tartrazine sensitivity (75 and 150 mg caps), elderly, prolonged therapy

Interaction:

Drugs

Food: Decreased clindamycin concentrations with diet foods containing sodium cyclamate

Kaolin-pectin: Decreased clindamycin concentrations

Warnings:

Adverse Effects:

Lactations:

PREGNANCY AND LACTATION: Pregnancy ; excreted into breast milk; compatible with breast feeding

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

GI: Abdominal pain, anorexia, diarrhea, increased

AST, ALT, bilirubin, alk phosphatase; jaundice, nausea, pseudomembranous colitis, vomiting, weight loss

GU: Urinary frequency, vaginitis, vulvar irritation

HEME: Agranulocytosis, eosinophilia, leukopenia, thrombocytopenia

SKIN: Abscess at inj site, erythema, pain, pruritus, rash, urticaria

Patient And Carer Advice: