Indications & Dose:

Symptomatic relief of allergy such as hay fever, urticaria, food allergy, drug reactions Relief of itch associated with chickenpox

•  BY MOUTH

Child 1–23 months: 1 mg twice daily

Child 2–5 years: 1 mg every 4–6 hours; maximum  6 mg per day

Child 6–11 years: 2 mg every 4–6 hours; maximum 12 mg per day

Child 12–17 years: 4 mg every 4–6 hours; maximum 24 mg per day

Adult: 4 mg every 4–6 hours; maximum 24 mg per day

Elderly: 4 mg every 4–6 hours; maximum 12 mg per day  

• BY INTRAMUSCULAR INJECTION, OR BY INTRAVENOUS INJECTION

Child 1–5 months: 250 micrograms/kg (max. per dose 2.5 mg), repeated if necessary; maximum 4 doses per day

Child 6 months–5 years: 2.5 mg, repeated if necessary; maximum 4 doses per day

Child 6–11 years: 5 mg, repeated if necessary; maximum 4 doses per day

Child 12–17 years: 10 mg, repeated if necessary; maximum 4 doses per day

Adult: 10 mg, repeated if necessary; maximum 4 doses per day

Emergency treatment of anaphylactic reactions

• BY INTRAMUSCULAR INJECTION, OR BY INTRAVENOUS INJECTION

Child 1–5 months: 250 micrograms/kg (max. per dose 2.5 mg), repeated if necessary;maximum 4 doses per day

Child 6 months–5 years: 2.5 mg, repeated if necessary; maximum 4 doses per day

Child 6–11 years: 5 mg, repeated if necessary; maximum 4 doses per day

Child 12–17 years: 10 mg, repeated if necessary; maximum 4 doses per day

Adult: 10 mg, repeated if necessary; maximum 4 doses per day

OR

Adult

Orally: 4 mg (one) tablet, 4-6 hourly, max; 6 daily

SYP: 10 ml 4-6 hourly; max 60ml daily

INJ:5-10 mg im/iv

Children

Tab under 6 years not recommended

6-12 years; 1/2 tab 4-6 hourly, max; 3 daily

Syp under 1 years not recommended

1-2 years; 2.5ml twice daily

2-5 years 2,5ml 4-6 hourly, max; 15ml daily

6-12 years, 5ml 4-6 hourly max; 30ml daily.

By i.m: 10-20mg repeated if required: max 40mg in 24 hours

By slow i.v: over 1 minute 10-20mg.

Under 1 year not recommended.

Contraindications:

Cautions:

Precautions:

Increased intraocular pressure (angle-closure glaucoma), renal disease, cardiac disease, hypertension, bronchial asthma, seizure disorder, stenosed peptic ulcers, hyperthyroidism, prostatic hypertrophy, bladder neck obstruction, elderly

Interaction:

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

CNS: Anxiety, confusion, dizziness, drowsiness, euphoria, fatigue, neuritis, paresthesia, poor coordination

EENT: Blurred vision, dilated pupils. dry nose, throat; tinnitus

GI: Anorexia, diarrhea, dry mouth, nausea

GU: Dysuria, frequency, retention

HEME: Agranulocytosis, hemolytic anemia, thrombocytopenia 

RESP: Chest tightness, increased thick secretions, wheezing

SKIN: Photosensitivity

Patient And Carer Advice: