Indications & Dose:

For the improvement of neurological deficits in patients with amyotrophic lateral sclerosis. Parkinsonism and ataxia of spinocerebellar degeneration. Assessment of thyroid function and thyroid stimulating hormone reserve.

DOSAGE:

Amyotrophic lateral sclerosis:

ADULTS: 200-500mcg by IV infusion at 2 to 19mcg per minute. Assessment of thyroid function and thyroid stimulating hormone reserve:

ADULTS: IV inj 200mcg.
CHILDREN: 1mcg/kg.

Contraindications:

Cautions:

Precautions:

Severe hypopituitarism, myocardial ischaemia, obstructive airway disease, pregnancy

Interaction:

Dopamine, bro-mocriptine, chlorpromazine, thiori-dazine, asprin, glucocorticosteroid, theophylline, lithium ranitidine, oestrogens

Warnings:

Adverse Effects:

After rapid IV administration, desire to micturate, flushing, dizziness, nausea, strange taste; transient increase in pulse rate and blood pressure; rarely bronchospasm.

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: