Clinical Pharmacology Details


Brivaracetam


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Indications & Dose:

Indicated for partial-onset seizures


50 mg PO/IV q12hr initially based on individual patient tolerability and therapeutic response, adjust dose between to 25-100 mg PO/IV BID (50-200 mg/day)


Injection may be used for patients when oral administration is temporarily not feasible clinical study experience with injection is limited to 4 consecutive days of treatment

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Adverse Effects:

Somnolence and sedation  


Dizziness 


Fatigue  


Nausea and vomiting  


Cerebellar coordination and balance disturbances  


Irritability  


Constipation  Pregnancy and Lactation


Pregnancy


No adequate and well controlled studies in pregnant women .

Lactations:

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Counselling:

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Patient And Carer Advice: