Pentoxifylline (Oxpentifylline)

Indications & Dose:

Peripheral vascular disease | Venous leg ulcer (adjunct)

BY MOUTH

Adult: 400 mg 2-3 times a day

Contraindications:

Acute myocardial infarction . cerebral haemorrhage . extensive retinal haemorrhage . severe cardiac arrhythmias

Side Effects:

Rare Angina . hypotension

Very rare Bleeding

Frequency not known Agitation . diarrhoea . dizziness . flushing . headache . intra-hepatic cholestasis . nausea . sleep disturbances .tachycardia .thrombocytopenia . vomiting

PREGNANCY Avoid .

BREAST FEEDING Present in milk-Use only if potential benefit outweighs risk.

HEPATIC IMPAIRMENT Advises reduce dose in severe impairment.

RENAL IMPAIRMENT Reduce dose by 30-50% if eGFR less than 30 mL/minute/1.73 m2.

Cautions:

Avoid in acute porphyrias. coronary artery disease . hypotension

Precautions:

-

Interaction:

-

Warnings:

-

Adverse Effects:

-

Lactations:

-

Special Precautions:

-

Counselling:

-

Side Effects Or Adverse Reactions:

-

Patient And Carer Advice:

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