Empagliflozin with metformin

Indications & Dose:

Type 2 diabetes mellitus not controlled by metformin alone or by metformin in combination with other antidiabetic drugs or insulin

▶BY MOUTH

▶Adult 18–84 years: 5/850–5/1000 mg twice daily, based on patient’s current metformin dose, increased if necessary to 12.5/850–12.5/1000 mg twice daily

▶BY MOUTH

▶Adult 85 years and over: Initiation not recommended

DOSE ADJUSTMENTS DUE TO INTERACTIONS

Dose of concomitant insulin or drugs that stimulate insulin secretion may need to be reduced.

DOSE EQUIVALENCE AND CONVERSION

▶The proportions are expressed in the form "x"/"y" where "x" and "y" are the strengths in milligrams of empagliflozin and metformin respectively.

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