Silver Sulphadiazine

Indications & Dose:

INDICATIONS: Prophylaxis and treatment of infection in burn wounds; as an adjunct to shortterm treatment of infection in leg ulcers and pressure sores; as an adjunct to prophylaxis of infection in skin graft donor sites and extensive abrasions; for conservative management of fingertip injuries.

DOSE

Adult: Apply in layers 3-5 mm thick, change dressing three times a week for ulcers and daily for burns

Children: Under 3 months not recommended

Contraindications:

Sensitivity to sulphonamides, not recommended for neonates & pregnancy.

Side Effects:

Allergic reactions including burning, itching and rashes, argyria reported following prolonged use, leucopenia reported (monitor blood levels).

Cautions:

Precautions:

Hepatic and renal impairment; G6PD deficiency, may in- activate enzymatic debriding agents therefore concomitant use may be inappropriate, for large amounts.

Breast-feeding: Use with caution. Avoid in neonates.

Old age: May be used.

Interaction:

Drugs 

Same as sulphonamides. Topical proteolytic enzymes: Silver may inactivate such enzymes.

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: