Fluorometholone+ Gentamicin

Indications & Dose:

Treatment of corticosteroid-responsive inflammation of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe.

Shake well before using. Instill one drop into the conjunctival sac two to four times daily.

During the initial 24 to 48 hours, the dosing frequency may be increased to one application every

four hours. Care should be taken not to discontinue therapy prematurely.

If signs and symptoms fail to improve after two days, the patient should be re-evaluated .

The dosing may be reduced, but care should be taken not to discontinue therapy prematurely. In chronic conditions, withdrawal of treatment should be carried out by gradually decreasing the frequency of applications

Contraindications:

Vral diseases of the cornea and conjunctiva, including epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, and varicella, and also in mycobacterial infection of the eye, and fungal diseases of ocular structures. Hypersensitivity to any of the ingredients of this preparation and to other corticosteroids.

Side Effects:

Cautions:

Precautions:

If inflammation or pain persists longer than 48 hours or becomes aggravated, the patient should

be advised to discontinue use of the medication and consult a physician.

Pregnancy: Teratogenic effects. Pregnancy Category C

Nursing Mothers

It is not known whether topical ophthalmic administration of corticosteroids could result in

sufficient systemic absorption to produce detectable quantities in human milk. Systemicallyadministered corticosteroids appear in human milk and could suppress growth, interfere with endogenous corticosteroid production, or cause other untoward effects. Because of the potential for serious adverse reactions in nursing infants from fluorometholone, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of

the drug to the mother.

ediatric Use; Safety and effectiveness in infants below the age of two years have not been established.

Geriatric Use: No overall differences in safety or effectiveness have been observed  elderly and younger patients

Interaction:

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

 Elevation of intraocular pressure (IOP) with possible development of glaucoma and infrequent optic nerve damage, posterior subcapsular cataract formation, and delayed wound healing.

The development of secondary ocular infection (bacterial, fungal and viral) has occurred. Fungal

and viral infections of the cornea are particularly prone to develop coincidentally with long-term

applications of steroids. The possibility of fungal invasion should be considered in any

persistent corneal ulceration where steroid treatment has been used.

Transient burning and stinging upon instillation and other minor symptoms of ocular irritation.

Allergic reactions; foreign body sensation; erythema of eyelid; eyelid edema/eye swelling; eye discharge; eye pain;eye pruritus; lacrimation increased; rash; taste perversion; visual disturbance (blurry vision); and visual field defect.

Patient And Carer Advice: