Clinical Pharmacology Details


Lindane


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Indications & Dose:

Pediculus capitis (head lice), Pediculus pubis (crab lice) and their ova; Sarcoptes scabiei (scabies)


DOSE


Adult and Child


Lotion: (Crab lice) apply sufficient quantity only to cover the hair and skin of the pubic area and adjacent infested areas, leave in place for 12 hr then wash thoroughly, may repeat in 7 days if necessary, treat sexual contacts concurrently; (head lice) apply a sufficient quantity to cover only the affected area, rub into scalp, and leave in place for 12 hr then wash thoroughly, may repeat in 7 days if necessary; (scabies) make total body application from neck down, leave on 8-12 hr (adults), 6-8 hr (children), 6 hr (infants), remove by thorough washing, 60 ml usually sufficient for adults


• Shampoo: (Head lice and crab lice) apply a sufficient quantity to dry hair, work thoroughly into hair and allow to remain in place for 4 min, add small quantities of water until a good lather forms, rinse hair thoroughly and towel briskly; comb with a fine-toothed comb or use tweezers to remove any remaining nits or nit shells, retreatment not usually necessary; short hair requires approximately 30 ml, long hair 60 ml


DOSE: For scabies: Apply thinly over whole body omitting head and neck wash off using cool water after 24 hours repeat if necessary after 7 days. .
For crab lices: Apply to dry hair, leave for 4 minute add water to produce lather, rinse towel dry comb

Contraindications:

Premature neonates, seizure disorder

Side Effects:

Cautions:

Precautions:

Children, infants, avoid contact with eyes; inflammation of skin, abrasions, or breaks in skin

Interaction:

Warnings:

Adverse Effects:

Lactations:

Use no more thin twice during a pregnancy; amounts excireted in breast milk probably clinically insignificant

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

CNS: Dizziness, seizures, stimulation
SKIN: Eczematous eruptions due to irritation

Patient And Carer Advice: