Typhoid Vaccines

Indications & Dose:

Prevention of typhoid fever in adults and children over 5 years.

DOSE One cap. on day 1, 3 and 5 irres-pective of age and weight. Capsule has to be taken one hour before meal with cold or lukewarm milk or water.

INDICATIONS: Prophylactic immunization of adults and children over 6 years against typhoid feve

DOSE 

1 single dose of 0.5ml s.c or i.m.

(b) Oral Typhoid Vaccine Contains the attenuated strain Ty 21a of Salmonella Typhii. The attenuation is due to the absence of enzyme uridine diphosphate galactose-4 epimerase which is essential for the production of the lypo polysacchride ‘O’ antigen. The absence of this enzyme makes Ty 21a highly immunogenic. This oral vaccine acts in a way similar to the typhoid bacillus but instead of the fever, give immunity against it. 

Contraindications:

Blood transfusion or immunoglobulin injection within previous three months, concurrent therapy with ACTH or corticosteroid, irradiation, alky-lating agents or antimetabolitis. Blood dyscrasias, leukaemia, malignant neoplasm affecting bone marrrow & lymphatic systems. Primary immunodefficiency states, acute febrile infections. Hypersensi-tivity.

PREGNANCY. Children below 5 years contraindicated.

Special note: Does not afford protection against Salmonella Paratyphii A or B.

CONTRAINDICATIONS: Acute febrile illness, acute intestinal infection. Congenital or acquired immuno deficiency. 

Side Effects:

Slight local pain, fever, rash.

SIDE EFFECTS: Fever and/or mild G.I. effects. 

Cautions:

Precautions:

Preferable to delay the vaccination in fever/acute infection. 

PRECAUTIONS: Sulfonamides known to be active against S. typhii should not be given concomitantly. 

Interaction:

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: