Fluticasone Furoate

Indications & Dose:

treatment of symptoms of seasonal and perennial allergic rhinitis in adults and children =2 years.

DOSAGE AND ADMINISTRATION: 

Adults and adolescents =12 years: 110 mcg (2 sprays per nostril) once daily. 
Children 2-11 years: 55 mcg (1 spray per nostril) once daily

Contraindications:

None.

Side Effects:

Cautions:

Precautions:

Interaction:

DRUG
Potent inhibitors of CYP3A4 may increase exposure to fluticasone furoate.

Co-administration of ritonavir is not recommended. Use caution with co-administration of other potent CYP3A4 inhibitors, such as ketoconazole.

USE IN SPECIFIC POPULATIONS:Hepatic impairment may increase exposure to fluticasone furoate. Use with caution in patients with severe hepatic impairment

Warnings:

Epistaxis, nasal ulceration, Candida albicans infection, nasal septal perforation, impaired wound healing. Monitor patients periodically for signs of adverse effects on the nasal mucosa. Avoid use in patients with recent nasal ulcers, nasal surgery, or nasal trauma. Development of glaucoma or posterior subcapsularcataracts. Monitor patients closely with a change in vision or with a history of increased intraocular pressure, glaucoma, and/or cataracts. Potential worsening of existing tuberculosis; fungal, bacterial, viral, or parasitic infections; or ocular herpes simplex. More serious or even fatal course of chickenpox or measles in susceptible patients. Use caution in patients with the above because of the potential for worsening of these infections. Hypercorticism and adrenal suppression with very high dosages or at the regular dosage in susceptible individuals. If such changes occur, discontinue Nasal Spray slowly. Potential reduction in growth velocity in children. Monitor growth routinely in pediatric patients receiving Nasal Spray.

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

The most common adverse reactions (>1% incidence) included headache, epistaxis, pharyngolaryngeal pain, nasal ulceration, back pain, pyrexia, and cough.

Patient And Carer Advice: