Clinical Pharmacology Details


Exemestane


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Indications & Dose:

Adjuvant treatment of oestrogen-receptorpositive early breast cancer in postmenopausal women following 2–3 years of tamoxifen therapy | Advanced breast cancer in postmenopausal women in whom antioestrogen therapy has failed 



Adult: 25 mg daily

Contraindications:

Not indicated for premenopausal women

Side Effects:

Common or very common Abdominal pain . alopecia . anorexia . constipation . depression . dizziness . dyspepsia . fatigue . headache . hot flushes . insomnia . nausea . rash . sweating . vomiting


Uncommon Asthenia . drowsiness . peripheral oedema


Rare Leucopenia . thrombocytopenia


PREGNANCY Avoid.
BREAST FEEDING Avoid.
HEPATIC IMPAIRMENT Manufacturer advises caution.
RENAL IMPAIRMENT Manufacturer advises caution. 

Cautions:

Precautions:

Interaction:

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: