Bicalutamide

Indications & Dose:

Advanced prostate cancer in combination with a gonadorelin analogue or surgical castration; localised or locally advanced prostate cancer either alone or as adjuvant treatment.

DOSE: Advanced prostate cancer, with orchidectomy or gonadorelin therapy, 50mg daily (in gonadorelin therapy, started 3 days beforehand. Localised or locally advanced prostate cancer, 150mg once daily

Contraindications:

Side Effects:

nausea, vomiting, diarrhoea, asthenia, gynaecomastia, breast tenderness, hot flushes, pruritus, dry skin, alopecia, hirsutism, decreased libido, impotence, weight gain; rarely abdominal pain, cardiovascular disorders (including angina, heart failure and arrhythmias), depression, dyspepsia, haematuria, cholestasis, jaundice, thrombocytopenia. 

Cautions:

Hepatic impairment, also consider periodic liver function tests

Precautions:

Interaction:

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: