Temozolomide

Indications & Dose:

Treatment of adult patients with refractory (first relapse) anaplastic astrocytoma who have experienced disease progression on nitrosourea and procarbazine.:
Adults: 150-200 mg/square meter/day for 5 days, repeat every 28 days. 

Contraindications:

Side Effects:

Cautions:

Precautions:

 Hepatic & renal imapirment, elderly

Interaction:

Warnings:

Adverse Effects:

Peripheral oedema, headache, fatigue, convulsions, dizziness, fever, GI upsets, neutropenia, thrombocytopenia, anaemia, paresthesia. 

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: