Imatinib

Indications & Dose:

Chronic myeloid leukaemia in chronic phase after failure of interferon alfa, or in accelerated phase, or in blast crisis. Kit-positive unresectable or metastatic malignant gastrointestinal stromal tumors (GIST) l

• BY MOUTH

Adults: Doses of 400 mg or 600 mg should be administered once daily, whereas a dose of 800 mg should be administered as 400 mg twice a day with a meal and a large glass of water.
Children: The safety and efficacy of in patients under the age of 18 years have not been established.

Contraindications:

patients with hypersensitivity to imatinib or to any other component. 

Side Effects:

Cautions:

Precautions:

Renal impairment, GI irritation, Hemorrhage, hematologic toxicity, hepatotoxicity

Interaction:

Warnings:

Adverse Effects:

Lactations:

Advised to avoid becoming pregnant. 

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

 Nausea, vomiting, diarrhoea, oedema, muscle pain, and headache. 

Patient And Carer Advice: