Pilocarpine

Indications & Dose:

Ophth: open-angle glauconla, chronic angleclosure glaucoma, acute angleclosure glaucoma (in combination with other agents to decrease lOP before surgery), reversal of mydriasis, pre and postoperative increased IOP; oral: xerostomia from salivary gland hypofuriction secondary to radiotherapy for head and neck cancer

DOSAGE

Adult: Instill frequently 1-2 drops as reqd. 
Children: Same dose – Occlude lacrimal sac during instillation to prevent systemic effect. 

Contraindications:

Acute iritis, or other condition where acute miosis undesirable.

Side Effects:

Cautions:

Precautions:

Bronchial asthma, hypertension, - bradycardia, hyperthyroidism, CV disease, biliary disease, renal colic (nephrolithiasis), epilepsy, parkinsonism, asthma 

Interaction:

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

CNS: Headache
CV: AV block, bradycardia, dysrhythmia, hypertension, hypotension, shock, tachycardia
EENT: Blurred vision, conjunctival irritation. (Ocusert), eye pain with change in focus, retinal detachment. stinging, tearing, twitching of eyelids
GI: Abdominal cramps, diarrhea, nausea, vomiting
GU: Bladder tightness, frequency, urgency
RESP: Bronchospasm 

Patient And Carer Advice: