Clinical Pharmacology Details


Chloramphenicol


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Indications & Dose:

It is a broad spectrum antibacterial drug.


INDICATIONS: Bacterial infection in otitis externa, chronic otitis media, pre and post aural or mastoid surgery.


DOSE


Adults : 2-3 drops, 3-4 times daily. Children: 1-2 drops thrice daily


 

Contraindications:

Side Effects:

Sensitivity reactions to vehicle

Cautions:

Precautions:

 If sensitivity reaction occurs after topical instillation discontinue treatment. Prolonged use

Interaction:

Warnings:

Adverse Effects:

Lactations:

Should not be given to pregnant or lactating women and to new-born babies 

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Shortly after application a slight burning sensation and bitter taste in the mouth may occur. Allergic reactions in the form of palpebral eczema have been rarely reproted. Partially irreversible blood dyscrasias (aplastic anaemia, pancytopenia, leucopenia, thrombocytopenia, agranulocytosis) have been rately observed in association with topical use of Chloramphenicol. 

Patient And Carer Advice: