Rubefacients and other topical antirheumatics

Indications & Dose:

Topical analgesics are indicated for the temporary relief of minor aches and pains of muscles and joints due to muscle strains, sprains and bruises or overexertion, as an adjunct in the manage-ment of minor stiffness or soreness associated with arthritis, rheumatism, Lumbago, fibrositis, sciatica and stiffneck.

The goal with topical NSAID therapy is to achieve high local concentration at the site of application and a low plasma concentration. This method of drug administration minimises the G.I. and systemic adverse effects of NSAID’s

 DOSE Apply to the affected area 2-3 times daily. Rubbing or massaging should be  usually avoided. 

Contraindications:

Hypersensitivity. 

Side Effects:

Dermatitis, local irritation, erythema, photosensitivity, pruritus

Cautions:

Apply with gentle massage only. Avoid contact with eyes, mucous membranes, and inflamed or broken skin; discontinue if rash develops. Hands should be washed immediately after use. Not for use with occlusive dressings. Topical application of large amounts may result in systemic effects including hypersensitivity and asthma (renal disease has also been reported). Not generally suitable for CHILDREN.

HYPERSENSITIVITY. For NSAID hypersensitivity and asthma

PHOTOSENSITIVITY. Patients should be advised against excessive exposure to sunlight of area treated in order to avoid possibility of photosensitivity. 

Precautions:

Topical analgesics containing salicylates are to be avoided or used with caution in patients of Vitamin K deficiency, hypothrombinemia, liver disease, before surgery. It is NOT to be applied on wounds are broken skin. To be used under medical supervision during

Interaction:

Warnings:

Adverse Effects:

Lactations:

These preparations are for external use only.

As the drugs in topical analgesics may produce irritation they should not be applied near eyes, on mucus membrane or on inflamed skin.

The principal drugs used in topical anal-gesics are salicylates, capsicum, nicotina-tes, histamine. Camphor and menthol are also added in some preparations which produce a feeling of coolness. These topical agents also contain drugs like Ibuprofen, Mephenesin, Diclofenac, Oxyphenbutazone.

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: