Amino Acids

Indications & Dose:

Amino acid deficiency.
Dose: One tab daily.
Children: Not recommended

Contraindications:

Contraindicated in patients with anuria; patients with inborn errors of amino acid metabolism, such as maple syrup urine disease and isovaleric academia; and patients with severe uncorrected electrolyte or acid-base imbalances, hyperammonemia, or decreased circulating blood volume. Use cautiously in neonates (especially those with low birth weight), children, and patients with impaired renal, hepatic, or cardiac function. 

Side Effects:

Cautions:

Precautions:

Interaction:

Drug-drug. Acidic I.V. solutions for total parenteral nutrition
(TPN): May release bicarbonate as gas. Avoid use together. Amino acid solutions: May be incompatible.
Don’t mix together.
Blood: May cause pseudoagglutination. Don’t give with blood. Electrolytes, heparin, insulin, supplementary vitamins,
trace minerals: May be added cautiously when needed. Don’t give other drugs via central venous catheter.
Folic acid: Calcium salts precipitate as calcium folate. Avoid use together.
Sodium bicarbonate: May precipitate calcium and magnesium and decrease activity of insulin and vitamin B complex with vitamin C. Avoid use together.
Tetracycline: May reduce protein-sparing effects of infused amino acids. Use together cautiously Vitamin K. May be incompatible. Give separately

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

CNS: fever.
CV: flushing, edema, thrombophlebitis, thrombosis.
GI: nausea.
GU: glycosuria, osmotic diuresis.
Hepatic: hepatic dysfunction.
Metabolic: alkalosis, electrolyte imbalances, hyperammonemia, hyperglycemia, hyperosmolar hyperglycemic nonketotic syndrome, hypophosphatemia, metabolic acidosis, rebound hypoglycemia (when long-term infusions are abruptly stopped), weight gain.
Musculoskeletal: osteoporosis.
Skin: tissue sloughing at infusion site caused by extravasation.
Other: catheter sepsis, hypersensitivity reactions

. Effects on lab test results

May increase ammonia, BUN, serum creatinine, and liver enzyme levels. May decrease phosphate, magnesium, and potassium levels. May increase or decrease glucose levels. 

Patient And Carer Advice: