Levocarnitine

Indications & Dose:

Primary carnitine deficiency due to inborn errors of metabolism

• BY MOUTH

Adult: Up to 200 mg/kg daily in 2–4 divided doses; maximum 3 g per day

• BY SLOW INTRAVENOUS INJECTION

Adult: Up to 100 mg/kg daily in 2–4 divided doses, to be administered over 2–3 minutes

Secondary carnitine deficiency in haemodialysis patients

• INITIALLY BY SLOW INTRAVENOUS INJECTION

Adult: 20 mg/kg, to be administered over 2–3 minutes, after each dialysis session, dosage adjusted according to plasma-carnitine concentration, then (by mouth) maintenance 1 g daily, administ 

Contraindications:

The patient should avoid levocarnitine if allergy to it

Side Effects:

Cautions:

Precautions:

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.
PREGNANCY: Reproductive studies have been performed in animals and have revealed no evidence of impaired fertility or harm to the fetus due to Levocarnitine. There are, however, no adequate and well controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.
NURSING MOTHERS: In nursing mothers receiving levocarnitine, any risks to the child of excess carnitine intake need to be weighed against the benefits of levocarnitine supplementation to the mother. Consideration may be given to discontinuation of nursing or of levocarnitine treatment 

Interaction:

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Transient nausea and vomiting. Less   body odor, nausea, and gastritis

Patient And Carer Advice: