Clinical Pharmacology Details


Calcium gluconate


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Indications & Dose:

Severe acute hypocalcaemia or hypocalcaemic tetany INITIALLY
BY SLOW INTRAVENOUS INJECTION Adult:
Initially 10–20 mL, calcium gluconate injection 10% (providing approximately 2.25–4.5 mmol of calcium) should be administered with plasma-calcium and ECG monitoring, and either repeated as required or, if only temporary improvement, followed by a continuous intravenous infusion to prevent recurrence, alternatively (by continuous intravenous infusion), initially 50 mL/ hour, adjusted according to response, infusion to be administered using 100mL of calcium gluconate 10% diluted in 1 litre of glucose 5% or sodium chloride 0.9% Acute severe hyperkalaemia (plasma potassium potassium concentration above 6.5 mmol/litre or in the presence of ECG changes) BY SLOW INTRAVENOUS INJECTION Adult: 10–20 mL, calcium gluconate 10% should be administered, dose titrated and adjusted to ECG improvement Calcium deficiencyMild asymptomatic hypocalcaemia
BY MOUTH Adult
: Dose according to requirements

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