Iron Sucrose Complex

Indications & Dose:

Patients who cannot tolerate oral iron therapy, patients who cannot sufficiently absorb orally administered iron:

Adults & Elderly: l

• BY IV INFUSION

5–10ml  (100 to 200 mg iron) twice or three times a week depending on the haemoglobin level.

Children:

0.15ml /kg body weight (- 3mg iron/kg bw) twice or three times a week depending on the haemoglobin level.

Maximum tolerated single dose

Adults and the"Elderly:

As injection: 10ml  (200 mg iron) injected in at least 10 min. As infusion: if the clinical situation demands the single dose may be increased to 0.35ml /kg body weight (=7mg iron/kg bw) not exceeding 25ml (500mg iron), diluted in 500ml 0.9% w/v NaCl infused over at least 3.5h, once a week.

Children: 0.35ml /kg body weight (= 7mg iron/kg bw) diluted in 0.9% w/v NaCl and infused over at least 3.5h, once a week. 

Contraindications:

Side Effects:

Very rarely : Anaphylactic like reactions .
Occassionally : Metallic taste, headache, nausea, vomiting and hypotension.parasthesia, abdominal disorders, muscular pain, fever, urticaria, flushing, oedema of the extremities and anaphylactoid (pseudoallergic) reactions. In the region of the puncture vein, phlebitis and venous spasm have been observed.Stability of Iron Sucrose in comparison to transferrin, a competitive exchange of iron to transferrin was observed. This results in an iron transport of approx. 31mg Fe(III) 

Cautions:

Precautions:

Interaction:

Drugs
Oral iron is reduced. Therefore an oral iron therapy should at least be started 5 days after the last injection.

Warnings:

Adverse Effects:

Lactations:

First three months has to be discouraged. During the second and third term the application has to be done with caution. Non metabolised Iron Sucrose is unlikely to pass into breast milk. 

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: