Lisuride

Indications & Dose:

As dopamine agonist in: Parkinsons disease. As prolectin inhibitor: primary & secondary lactation mastitis, galactorrhoea, reduction excessive milk production, amenorrhoea, luteal insufficiency, prolectin  induced infertility, if women disturbances of libido or potency of man.

DOSE: Initially 200mcg at bedtime with food increased as necessary at weekly interval to 200mcg twice daily (midday & at bedtime) further increase made by adding 200 mcg each week first to the bedtime dose then to midday dose & finally to morning dose max. 5mg daily in 3 divided doses after food.

Contraindications:

Severe disturbances of peripheral circulation, coronary insufficiency.

Side Effects:

Nausea, vomiting, dizziness, headache, leathargy, mailaise, drowsiness, psycotic reaction (hallucinations), occassionally severe hypotension & abdominal pain, rashes, constipation, Raynaudis phenomena. 

Cautions:

History of pitiutory tumor, psychotic disturbances, pregnancy, porphyria, hypotention. 

Precautions:

Interaction:

Drugs
Neuroleptics and other dopamine antagonist (e.g. haloperidol, sulpiride metaclopramide, chlorpromazine) ergot alkaloids (e.g. methyl ergometrin). 

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: