Nalidixic Acid

Indications & Dose:

Urinary tract infections. Gastrointestinal infections due to Gram-negative organisms.

DOSAGE:

Urinary tract infections:

ADULTS: Acute infections, 1 gm four times daily for min, 7 day. Chronic infections, 500mg four times daily.

CHILDREN: Under 3 month, not recommended; 3 months- 12 years, up to 50mg/kg body-wt. daily. GI infections:

ADULTS: 500mg-1 gm four times daily.

CHILDREN: Under 3 months, not recommended; 3 months-12 years, up to 50mg/kg daily. 

Contraindications:

History of convulsive disorders. Porphyria.

Side Effects:

Cautions:

Precautions:

 Liver disease, severe kidney dysfunction. Avoid unnecessary exposure; to sunlight. Pregnancy and lactation. 

Interaction:

Anticoagulants, probenecid, antibacterials. 

Warnings:

Adverse Effects:

GI, CNS and visual disturbances. Skin rashes, blood dyscrasias, convulsions, photosensitivity, intracranial hypertension. 

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: