Clinical Pharmacology Details


Estradiol valerate + Norgestrel


View Drug Forms

Indications & Dose:

Irregularities of the menstrual cycle; primary and secondary amenorrhoea; pre-and postmenopausal symptoms; deficiency symptoms after oophorectomy or radilogical castration for noncarcinomatous diseases.


DOSAGE:


Adults: 1 estradiol tab daily for 11 days then 1 combined tab daily for 10 days followed by 7 tabfree days Start on fifth day of menses.


Children: Not applicable. 

Contraindications:

Pregnancy, lactation, hypersensitivity to ingredients of the preparation, severe disturbances of liver function, jaundice or persistent itching during a previous pregnancy, previous or existing liver tumours, tumour of the uterus, ovaries or breast or a suspicion of such tumours, endometriosis, existing or previous thromboembolic processes, severe diabetes mellitus with vascular changes, sickle cell anaemia, disturbances of lipometabolism, a history of herpes of pregnancy, otosclerosis with deterioration during pregnancy, undiagnosed vaginal bleeding

Side Effects:

Cautions:

Precautions:

Interaction:

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: