Risedronate

Indications & Dose:

Adults : Paget’s Disease: BY MOUTH 35 mg dailyx2 months • Post menopausal  Osteoporosis (prophylaxis): • BYMOUTH PO 35 mg  once weekely on the same day of each week • Post menopausal women on systemic corticosteroids therapy: • BYMOUTH 5mg tab daily Child: Not recommended 

Contraindications:

Hypocalcemia

Side Effects:

CV: Chest pain
EENT: Iritis, dry eyes
GI: Diarrhea (20%); epigastric pain (rarely)
MS: Arthralgia, myasthenia 

Cautions:

Precautions:

Renal impairment, congestive heart failure, hyperphosphatemia (potential for increased tubular reabsorption of phosphate), liver disease, fever 

Interaction:

Drugs

Antacids, calcium: decreased absorption of risedronate Food: decreases bioavailability of risedronate by 50%

Warnings:

Adverse Effects:

Lactations:

Pregnancy category C; breast milk excretion unknown 

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: