Insulin Detemir

Indications & Dose:

Treatment of diabetes mellitus

DOSAGE:

Individual by once or twice daily subcutaneous injection. When given twice daily, the evening dose may be administered in the evening of at bedtime.Transfer from other insulins may require adjustment of dosage and timing of administration; monitor glucose during transfer and in initial weeks thereafter. Concurrrent short-acting insulin treatment may need to be adjusted. No studies in children below the age of 6 years. 

Contraindications:

Hypersensitivity to insulin detemir or excipients

Side Effects:

Cautions:

Precautions:

Interaction:

Warnings:

WARNINGS AND PRECAUTIONS FOR USE: 

Use of dosages which are inadequate.

Or discontinuation of treatment may lead to hyperglycemia and ketoacidosis  which are potentially lethal. Too much insulin, omission of a meal or strenuous exercise may lead to hypoglycemia. Redution of warning symptoms of hypoglycaemia  may be seen upon tightening

Control and also in patients with long-standing diabetes.Transferring to a new type or brand of insulin should be done under strict medical supervision. Careful monitoring is recommended in patients with severe hypoalbuminaemia. Should not be administered intravenously; avoid intramuscular administration; do not use in insulin infusion pumps. Avoid mixing of rapid-acting insulin. Contains metacresol, which may cause allergic reactions. Hypoglycemia may constitute a risk when driving or operating machinery. 

Adverse Effects:

Lactations:

No clinical experience in pregnancy and lactation; exercise precaution when prescribing to pregnant or lactating women.

UNDESIRABLE EFFECTS:

Common: Hypoglycaemia, injection site reactions, usually transitory.

Uncommon: Lipoglycemia; oedema and refraction anomalies on instituting therapy; allergic reactions; generalized hypersensitivity reactions are potentially lifethreatening; abrupt improvement in glycaemic control may be associated with worsening of diabetic retinopathy.

Rare: Acute painful neuropathy may be associated with rapid improvement in blood glucose control, usually reversible.

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: