Sitagliptin

Indications & Dose:

Type II diabetes mellitus.

• BY MOUTH

Adult Dosage: 100mg 24 hourly oral (take with or without food. If drug bothers your stomach, try taking it with food.

Children: Not Recommended.

Contraindications:

Trauma, Diabetic ketoacidosis, Insulin dependent diabetes mellitus, Severe infections, Type I diabetes mellitus. CONTRAINDICATIONS Diabetic ketoacidosis, hypersensitivity to sitagliptin or its components, type 1 diabetes 

Side Effects:

Cautions:

Precautions:

Interaction:

DRUGS

ACE inhibitors, disopyramide, fibric acid derivatives, fluoxetine, sulfonylureas: Possibly increased hypoglycemic effects beta blockers: Possibly prolonged hypogly-cemia or promotion of hyperglycemia digoxin: Slightly increased plasma digoxin level estrogens, oral contraceptives, phenytoin, progestins, thiazide diuretics, triamterene: Possibly decreased hypoglycemic effects

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

CNS: Headache
EENT: Nasopharyngitis
GI: Abdominal pain, acute pancreatitis, constipation, diarrhea, elevated hepatic enzymes, nausea, vomiting
GU: Acute renal failure, worsening renal function
RESP: Upper respiratory tract infection

SKIN: Cutaneous vasculitis, rash, StevensJohnson syndrome, urticaria
Other: Anaphylaxis, angioedema 

Patient And Carer Advice: