Alfentanil

Indications & Dose:

Spontaneous respiration: analgesia and enhancement of anaesthesia for short procedures

• BY INTRAVENOUS INJECTION

Adult: Initially up to 500 micrograms, dose to be administered over 30 seconds; supplemental doses

250 micrograms continued

Assisted ventilation: analgesia and enhancement of anaesthesia for short procedures

• BY INTRAVENOUS INJECTION

Adult: Initially 30–50 micrograms/kg, supplemental doses 15 micrograms/kg

Assisted ventilation: analgesia and enhancement of anaesthesia during maintenance of anaesthesia for longer procedures

• BY INTRAVENOUS INFUSION

Adult: Initially 50–100 micrograms/kg, dose to be administered over 10 minutes or as a bolus, followed by maintenance 30–60 micrograms/kg/ hour

Assisted ventilation: analgesia and suppression of

respiratory activity during intensive care for up to 4 days

• BY INTRAVENOUS INFUSION

Adult: Initially 2 mg/hour, adjusted according to response; usual dose 0.5–10 mg/hour, alternatively initially 5 mg in divided doses, to be administered over 10 minutes; dose used for more rapid initial control, reduce rate of administration if hypotension or bradycardia occur; additional doses of 0.5–1 mg may be given by intravenous injection during short painful procedures

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