Temazepam

Indications & Dose:

Insomnia

Adult:• 15-30 mg hs; in severe cases 60mg by mouth at night in exceptional circumstances; 7.5 mg hs may be sufficient for elderly or debilitated patients at bed time

Children: Not recommended

Contraindications:

Side Effects:

Cautions:

Precautions:

 Anemia, hepatic disease, renal disease, suicidal individuals, drug abuse, elderly, depression, psychosis, children <18 yr, acute narrow-angle glaucoma, seizure disorders, lung disease

Interaction:

Drugs

Cimetidine, disulfiram: Increased henzodiazepine levels

Clozapine: Possible increased risk of cardiorespiratory collapse

Ethanol: Adverse psychomotor effects

Rifampin: Reduced benzodiazepine levels.

Warnings:

Adverse Effects:

Lactations:

May cause sedation and poor feeding in nursing infant

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

CNS: Anxiety, confusion, daytime sedation dizziness, drowsiness, headache, irritability, lethargy, light-headedness, rebound insomnia

CV: Chest pain, hypotension, tachycardia

GI: Abdominal pain, anorexia, constipation, diarrhea heartburn, nausea, vomiting

HEME: Granulocytopenia (rare), leukopenia

RESP: Respiratory depression, sleep apnea

Patient And Carer Advice: