Tramadol hydrochloride

Indications & Dose:

Moderate to severe pain

 BY INTRAMUSCULAR INJECTION, OR BY INTRAVENOUS INJECTION, OR BY INTRAVENOUS INFUSION Adult: 50–100 mg every 4–6 hours, intravenous injection to be given over 2–3 minutes Moderate to severe acute pain

 BY MOUTH USING IMMEDIATE-RELEASE MEDICINES Child 12–17 years: Initially 100 mg, then 50–100 mg every 4–6 hours; Usual maximum 400 mg/24 hours Adult: Initially 100 mg, then 50–100 mg every 4–6 hours; Usual maximum 400 mg/24 hours Moderate to severe chronic pain

BY MOUTH USING IMMEDIATE-RELEASE MEDICINES Child 12–17 years: Initially 50 mg, then, adjusted according to response; Usual maximum 400 mg/24 hours Adult: Initially 50 mg, then, adjusted according to response; Usual maximum 400 mg/24 hours Postoperative pain

 BY INTRAVENOUS INJECTION Adult: Initially 100 mg, then 50 mg every 10–20 minutes if required up to total maximum 250mg (including initial dose) in first hour, then 50–100 mg every 4–6 hours, intravenous injection to be given over Moderate to severe pain (with modified-release 12-hourly preparations)

 BY MOUTH USING MODIFIED-RELEASE MEDICINES Child 12–17 years: 50–100 mg twice daily, increased if necessary to 150–200 mg twice daily, doses exceeding the usual maximum not generally required; Usual maximum 400 mg/24 hours Adult: 50–100 mg twice daily, increased if

necessary to 150–200 mg twice daily, doses exceeding the usual maximum not generally required; Usual maximum 400 mg/24 hours Moderate to severe pain (with modified-release 24hourly preparations)

 BY MOUTH USING MODIFIED-RELEASE MEDICINES Child 12–17 years: Initially 100–150 mg once daily, increased if necessary up to 400 mg once daily; Usual maximum 400 mg/24 hours Adult: Initially 100–150 mg once daily, increased if necessary up to 400 mg once daily; Usual maximum 400 mg/24 hours Moderate to severe pain

 BY MOUTH USING MODIFIED-RELEASE TABLETS Child 12–17 years: Initially 150 mg once daily, increased if necessary up to 400 mg once daily Adult: Initially 150 mg once daily, increased if necessary up to 400 mg once daily 

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