Oxycodone hydrochloride

Indications & Dose:

Postoperative pain | Severe pain | Moderate to severe pain in palliative care

  BY MOUTH

USING IMMEDIATE-RELEASE MEDICINES Adult: Initially 5 mg every 4–6 hours, dose to be increased if necessary according to severity of pain, some patients may require higher doses than the maximum daily dose; maximum 400 mg per day 

BY MOUTH USING MODIFIED-RELEASE MEDICINES Adult: Initially 10 mg every 12 hours (max. per dose 200 mg every 12 hours), dose to be increased if necessary according to severity of pain, some patients might require higher doses than the maximum daily dose continued  BY SLOW INTRAVENOUS INJECTION Adult:

1–10 mg every 4 hours as required   

BY INTRAVENOUS INFUSION Adult:

Initially 2 mg/hour, adjusted according to response   BY SUBCUTANEOUS INJECTION Adult: Initially 5 mg every 4 hours as required  BY SUBCUTANEOUS INFUSION Adult:

Initially 7.5 mg/24 hours, adjusted according to response Patient controlled analgesia (PCA) 

BY INTRAVENOUS INFUSION Adult:

(consult local protocol) 

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