Clinical Pharmacology Details


Metoclopramide hydrochloride


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Indications & Dose:

Symptomatic treatment of nausea and vomiting including that associated with acute migraine | Delayed (but not acute) chemotherapy-induced nausea and vomiting Radiotherapy-induced nausea and vomiting | Prevention of postoperative nausea and vomiting


BY MOUTH, OR BY INTRAMUSCULAR INJECTION, OR BY SLOW INTRAVENOUS INJECTION Adult (body-weight up to 60 kg): Up to 500 micrograms/kg daily in 3 divided doses, when administered by slow intravenous injection, to be given over at least 3 minutes Adult (body-weight 60 kg and above): 10 mg up to 3 times a day, when administered by slow intravenous injection, to be given over at least 3 minutes Hiccup in palliative care


 BY MOUTH, OR BY INTRAMUSCULAR INJECTION, OR BY SUBCUTANEOUS INJECTION


Adult: 10 mg every 6–8 hours Nausea and vomiting in palliative care


 BY MOUTH Adult: 10 mg 3 times a day


BY SUBCUTANEOUS INFUSION Adult: 30–100 mg/24 hours ANTIEMETICS AND ANTINAUSEANTS › SEROTONIN (5HT3) RECEPTOR ANTAGONISTS

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