Clinical Pharmacology Details


Orphenadrine hydrochloride


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Indications & Dose:

Parkinsonism | Drug-induced extrapyramidal symptoms (but not tardive dyskinesia)



Adult: Initially 150 mg daily in divided doses, then increased in steps of 50 mg every 2–3 days, adjusted according to response; usual dose 150– 300 mg daily in divided doses; maximum 400 mg per day


 Elderly: Preferably dose at lower end of range 


 

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