Clinical Pharmacology Details


Promazine hydrochloride


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Indications & Dose:

Short-term adjunctive management of psychomotor agitation



Adult: 100–200 mg 4 times a day


Agitation and restlessness in elderly



Elderly: 25–50 mg 4 times a day

Contraindications:

CNS depression . comatose states . phaeochromocytoma

Side Effects:

 Haemolytic anaemia


HEPATIC IMPAIRMENT Can precipitate coma; phenothiazines are hepatotoxic.


RENAL IMPAIRMENT Start with small doses in severe renal impairment because of increased cerebral sensitivity.


 

Cautions:

 Cerebral arteriosclerosis

Precautions:

Interaction:

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

Patient And Carer Advice: