Indications & Dose:
Major depression
Adult: Initially 75 mg daily in 2 divided doses, then increased if necessary up to 375 mg daily, dose to be increased if necessary at intervals of at least 2 weeks, faster dose titration may be necessary in some patients; maximum 375 mg per day continued’!
Adult: Initially 75 mg once daily, increased if necessary up to 375 mg once daily, dose to be increased if necessary at intervals of at least 2 weeks, faster dose titration may be necessary in some patients; maximum 375 mg per day
Generalised anxiety disorder
Adult: 75 mg once daily, increased if necessary up to 225 mg once daily, dose to be increased at intervals of at least 2 weeks; maximum 225 mg per day
Social anxiety disorder
Adult: 75 mg once daily, there is no evidence of greater efficacy at higher doses, increased if necessary up to 225 mg once daily, dose to be increased if necessary at intervals of at least 2 weeks; maximum 225 mg per day
Contraindications:
Concurrent use of MAOIs (at least 14 days should elapse between discontinuation of an MAOI and initiation of venlafaxine; at least 7 days should be allowed after stopping venlafaxine before starting an MAOI, age <18 yr
Side Effects:
Cautions:
Precautions:
Hypertension, anxiety, seizures, aggravation of bipolar disorder (0.5%)
Interaction:
Warnings:
Adverse Effects:
Lactations:
Excretion into breast milk unknown
Special Precautions:
Counselling:
Side Effects Or Adverse Reactions:
CNS: Anxiety, dizziess, insomnia, nervousness, seizures (0.3%), somnolence, tremor
CV: Hypertension (dose dependent; frequency 3%-13% ), vasodilation
EENT: Blurred vision, dry mouth, dysgeusia, mydriasis, tinnitus
GI: Anorexia, dyspepsia, nausea, vomiting
GU: Abnormal ejaculation or or gasm; impotence, urinary retention
RESP: Yawning SKIN: Sweating
MISC: Asthenia
Patient And Carer Advice:
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