ZAFIRLUKAST

Indications & Dose:

Prophylaxis of asthma

• BY MOUTH

Child 12–17 years: 20 mg twice daily

Adult: 20 mg twice daily 

Contraindications:

Side Effects:

Cautions:

 Elderly

PREGNANCY AND LACTATION: Pregnancy category C; breast milk excretion unknown 

Precautions:

Interaction:

Drugs

Astemizole. teifenadine: Zafirlukast inhibits drug metabolism with potential for cardiac dysrhythmias

Warfarin: Zafirlukast increases hypoprothrombinemic effect 

Warnings:

Adverse Effects:

Lactations:

Special Precautions:

Counselling:

Side Effects Or Adverse Reactions:

CNS: Headache (l8%), somnolence, weakness

EENT: Pharyngitis (20%), rhinitis (9%)

GI: Dry mouth, elevated transaminase levels, gastritis

RESP: Cough, exacerbation of asthma 

Patient And Carer Advice: